BDBM109233 2-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetrahydronaphthalen-2-yl)thiazole-4-carboxylic acid (Compound 4)::CHEMBL2398260
SMILES OC(=O)c1csc(n1)-c1ccc2CCCC(=NNc3nc4ccccc4s3)c2c1
InChI Key InChIKey=VQBHQKNPDJBYMG-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 109233
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Walter and Eliza Hall Institute of Medical Research
Affinity DataIC50: 4.00E+4nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Walter and Eliza Hall Institute of Medical Research
Affinity DataIC50: 8.00E+3nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair